There is a major significance of wine in the scripture from Genesis to Revelation. Each time wine is mentioned in the scripture it comes with a gift or something that helps you. As a matter of fact, when Jesus was about to depart, He served His disciples wine, thus signifying fellowship. In our world, wine is something that is opened during celebrations or occasions, hence it is a significant thing that brings people together. It connotes several things which include the revelation of the Spirit of God.